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Tag: Alcohol Use

Rodent ultrasonic vocalizations as biomarkers of future alcohol use: A predictive analytic approach

Published in:┬áCognitive, Affective, & Behavioral Neuroscience, Volume 18, Issue 1, 88-98 Abstract “Excessive alcohol consumption has a vast, negative impact on society. Rodent models have been successful in furthering our understanding of the biological underpinnings that drive alcohol consumption. Rodents emit ultrasonic vocalizations (USVs) that are each composed of several acoustic characteristics (e.g., frequency, duration, bandwidth, power). USVs reflect neurotransmitter activity in the ascending limb of the mesolimbic dopaminergic and cholinergic neurotransmitter systems and serve as noninvasive, real-time biomarkers of dopaminergic and cholinergic neurotransmission in the limbic system. In the present study, we recorded spontaneously emitted USVs from alcohol-na├»ve Long-Evans… Read More