Category: Cognitive, Affective, & Behavioral Neuroscience

Predicting risk decisions in a modified Balloon Analogue Risk Task: Conventional and single-trial ERP analyses

Published in: Cognitive, Affective, & Behavioral Neuroscience, Volume 18, Issue 1, 99-116 Abstract “Event-related potential (ERP) has the potential to reveal the temporal neurophysiological dynamics of risk decision-making, but this potential has not been fully explored in previous studies. When predicting risk decision with ERPs, most studies focus on between-trial analysis that reflects feedback learning, while within-trial analysis that could directly link option assessment with behavioral output has been largely ignored. Suitable task design is crucial for applying within-trial prediction. In this study, we used a modified version of the classic Balloon Analogue Risk Task (BART). In each trial of the… Read More

Dorsomedial prefrontal cortex 5-HT6 receptors regulate anxiety-like behavior

Published in: Cognitive, Affective, & Behavioral Neuroscience, Volume 18, Issue 1, 58-67 Abstract “The dorsomedial prefrontal cortex (dmPFC) plays a very important role in decision-related and anxiety-related information processing. It has enriched 5-HT6 receptors; however, the precise role of dmPFC 5-HT6 receptors in anxiety remains to be fully investigated. In this study, we injected dmPFC with the 5-HT6 receptor agonist EMD 386088 and antagonist SB 271046 using stereotactic technology. 5-HT6 receptor activation in mice increased time spent in the center area on the open-field test, increased exploration of the open arms on the elevated plus maze test, and increased ratio on… Read More

Thinking about others and the future: Neural correlates of perspective taking relate to preferences for delayed rewards

Published in: Cognitive, Affective, & Behavioral Neuroscience, Volume 18, Issue 1, 35-42 Abstract “We infer the thoughts and feelings of others by taking their perspectives. Similar processes could be used to understand how we will be affected by future events, by allowing us to take the perspective of our future self. In this paper, we test this idea using a previously presented framework for guiding predictions. The framework proposes that a shared neural mechanism is involved in controlling egocentric bias, both while shifting our perspective away from self and towards others, and while shifting our perspective from immediate to future perspectives.… Read More

Altered oscillatory brain dynamics of emotional processing in young binge drinkers

Published in: Cognitive, Affective, & Behavioral Neuroscience, Volume 18, Issue 1, 43-57 Abstract “Heavy episodic drinking, also termed binge drinking, is commonly practiced by young adults. It is accompanied by a range of cognitive, affective, and social problems, but the neural dynamics underlying changes in emotional functions is poorly understood. To investigate the behavioral and brain indices of affective processing as a function of binge drinking, young, healthy participants (23.3 ± 3.3 years) were assigned to two groups (n = 32 each) based on their drinking habits. Binge drinking (BD) participants reported drinking heavily with at least five binge episodes in the… Read More

Emotional enhancement of error detection—The role of perceptual processing and inhibition monitoring in failed auditory stop trials

Published in: Cognitive, Affective, & Behavioral Neuroscience, Volume 18, Issue 1, 1-20 Abstract “The first aim of the present study was to test whether arousing, aversive sounds can influence inhibitory task performance and lead to increased error monitoring relative to a neutral task condition. The second aim was to examine whether the enhancement of error monitoring in an affective context (if present) could be predicted from stop-signal-related brain activity. Participants performed an emotional stop-signal task that required response inhibition to aversive and neutral auditory stimuli. The behavioral data revealed that unpleasant sounds facilitated inhibitory processing by decreasing the stop-signal reaction time… Read More