Published in: Trends in Cognitive Sciences, Volume 22, Issue 3, 241-257 Abstract “Implicit in modern dimensional theories of psychiatric illness is the assumption that population variability and illness vulnerability are interchangeable constructs. Mounting evidence suggests that healthy variation is ubiquitous in natural populations, and must be interpreted in terms of cost–benefit tradeoffs. Psychiatric illnesses arise through a web of interactions linking brain function, behavior, and a lifetime of experiences. Research on illness etiology will only progress through the collection of comprehensive phenomic-level datasets. Large-scale collaborative efforts have begun to generate broad phenotypic batteries that encompass environmental and contextual factors, brain… Read More